EYA1 Antikörper (Internal Region)

Produktnummer ABIN487975

Dieser Ziege Polyklonal Antikörper erkennt spezifisch EYA1 in WB und EIA. Er zeigt eine Reaktivität gegenüber Human, Maus, Ratte, Rind (Kuh) und Hund.

Kurzübersicht für EYA1 Antikörper (Internal Region) (ABIN487975)

Target: EYA1 (Eyes Absent Homolog 1 (EYA1))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser EYA1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Produktdetails anti-EYA1 Antikörper

Bindungsspezifität: Internal Region

Spezifität: This antibody reacts to EYA1.

Kreuzreaktivität (Details): Species reactivity (expected):Mouse, Rat, Canine, Bovine.
Species reactivity (tested):Human.

Aufreinigung: Affinity chromatography

Immunogen: Peptide with sequence C-TDPTAEYSTIHSP, from the internal region of the protein sequence according to NP_742057.1, NP_000494.2, NP_742056.1.

Anwendungsinformationen

Applikationshinweise: Peptide ELISA: 1/16000. Western blot: Approx 55 kDa band observed in lysates of cell lline HEK293 (calculated MWof 60.5 kDa according to NP_742056.1). Recommended concentration: 1 - 3 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Details zu EYA1

Target: EYA1 (Eyes Absent Homolog 1 (EYA1))

Andere Bezeichnung: EYA1

Hintergrund: EYA1 (Eyes Absent Homolog 1) is a member of the eyes absent (EYA) family of proteins. EYA1 plays a role in transcriptional regulation during organogenesis. It is thought play a role in the development of the kidney, branchial arches, eye and ear. EYA1 is thought to coactivate SIX2, SIX4 and SIX5. EYA1 has intrinsic protein phosphatase activity, and dephosphorylates proteins such as Histone H2.AX phosphorylated on Y142. It is thought to play a role in promoting efficient DNA repair over apoptosis in response to genotypic stress.Synonyms: Eyes absent homolog 1

Gen-ID: 2138

NCBI Accession: NP_000494

UniProt: Q99502

Pathways: Sensory Perception of Sound, Positive Regulation of Response to DNA Damage Stimulus